A firefighter sustained minor injuries.
At 8:30 a.m. Sunday, fire crews were called to the 1800 block of Clarendon Avenue.
Upon arrival, firefighters located the two occupants and removed them from the home.
Both were taken to a nearby hospital, where they succumbed to their injuries, according to city of Middletown Communications Manager Clayton Castle.
The cause of the fire remains under investigation.
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