One man was pronounced dead at the scene and the other man was transported via CareFlight to Miami Valley Hospital in Dayton with critical injuries, according to Middletown police.
The names of both motorcyclists are being withheld until proper notifications are made, according to police.
Sgt. Ryan Rogers from the Middletown Division of Police said speed and impairment are possible causes for the crash. He said the motorcyclists were traveling southbound on Yankee when they collided.
Neither rider was wearing a helmet, he said.
The road remained closed for several hours during the investigation.
An autopsy is scheduled for Monday, according to the Butler County Coroner’s Office. Once the coroner has talked to the victim’s family, their name will be released, according to the coroner’s office.
This was at least the fourth fatal motorcycle crash and 23rd overall fatality on Butler County roads this year, according to the Ohio State Highway Patrol. There were six fatal motorcycle crashes last year and three in 2020, according to the OSP.
Through Aug. 7, there were 742 fatalities on Ohio roadways, 62 fewer than the same period last year.