Two occupants of the box truck were taken to the hospital with non-life-threatening injuries, and three firefighters were transported to the hospital as a precaution.
The crash is being investigated by West Chester police.
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A crash in West Chester Twp. sent multiple people to the hospital Saturday morning, according to Barbara Wilson with the West Chester Police Department.
The crash, which happened at approximately 6:15 a.m. at the intersection of Union Centre Boulevard and Beckett Road, involved a box truck and a West Chester fire engine.