Visitors who light up can be kicked off campus or arrested for criminal trespass, WCPO reports.
A committee of faculty, staff and students worked on the policy since then-President Santa Ono ordered an update last February.
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“Hopefully, this will make UC a healthier and cleaner place for everyone,” said Liz Aumann, UC benefits director and committee member.
She said UC will ramp up smoking cessation programs to help students, faculty and staff kick the habit.
UC joins Northern Kentucky University, Miami University, Thomas More College and Mount Saint Joseph University as completely tobacco-free campuses in Greater Cincinnati.
Miami University first banned smoking in 1993 in all public areas of buildings except designated smoking areas. In 2002, the university banned smoking in residence halls and within 25 feet of them. And in August of 2008, Miami's smoke-free policy expanded to include campus grounds. In 2013, the university banned smoking inside cars on campus.
Xavier University still allows outdoor smoking 15 feet or more from doors and windows and away from covered walkways.
Cincinnati State has four designated outdoor smoking areas but prohibits it elsewhere.