The plant closing is permanent, according to the company, which has more than 110 manufacturing facilities and 100 research-and-development centers worldwide.
In 2011, Israel-based flavors company Frutarom acquired Flavor Systems International of West Chester Twp., on Commerce Park Drive, for approximately $35 million.
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Frutarom USA Inc. announced in 2015 it planned to consolidate operations and production to create a U.S. headquarters at its existing West Chester facilities.
In 2018, IFF acquired Frutarom, one of the 10 largest flavoring companies in the world, for approximately $7.1 billion.
A company spokesperson could not be reached for comment Monday.