The Boeing 737 MAX 8 carrying 173 passengers and six crew members was on its way to Miami International Airport, American said.
Video aired by local media showed people sliding down the inflatable chute near the front of the plane while clutching luggage and small children. Some passengers, including at least one adult carrying a young child, tripped at the end of the slide and fell onto the concrete runway. Passengers were then taken to the terminal by bus.
One of the passengers was taken to a hospital with a minor injury, American Airlines said in its statement. Five people were evaluated for injuries at the scene but did not require hospitalization, Denver International Airport officials said.
"About halfway to takeoff speed, we hear a big bang and a pop," passenger Shaun Williams told KUSA-TV. "The pilot immediately started abort procedures for taking off. You could feel him start to hit the brakes."
Firefighters extinguished a fire on the aircraft, the Denver Fire Department said.
“All customers and crew deplaned safely, and the aircraft was taken out of service to be inspected by our maintenance team,” American said.
In a statement, the FAA said it will investigate.