Massaro joined WWE in 2005, entering the Raw Diva Search, which she won, according to Bleacher Report. She remained with the company through 2008.
"This is an incredible loss," wrestler Brandi Rhodes tweeted.
"This is just awful news -- Ashley Massaro is gone," longtime wrestler Mick Foley tweeted. "She was only 39. She lived in the same town as me."
"I have no words. Ashley was my tag partner at WrestleMania. My sometimes road wife. … I'm heartbroken for her family," Maria Kanellis Bennett tweeted.